Chloramphenicol.

نویسنده

  • T D Brock
چکیده

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Management of Typhoid Fever and Bacterial Meningitis by Chloramphenicol in Infants and Children

Chloramphenicol inhibits protein synthesis in bacteria and is usually bacteriostatic but is bactericidal against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis. Chloramphenicol penetrates all body tissues well. The cerebrospinal fluid concentration averages 60% of the serum level, while brain levels are 9 times higher because of high lipid solubility of this drug. Ch...

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Multidrug Resistance in Infants and Children

Bacterial infections may cause disease and death. Infants and children are often subject to bacterial infections. Antimicrobials kill bacteria protecting the infected patients andreducing the risk of morbidity and mortality caused by bacteria. The antibiotics may lose their antibacterial activity when they become resistant to a bacteria. The resistance to different antibiotics in a bacteria is ...

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Simultaneous Chloramphenicol and Florfenicol Determination by A Validated DLLME-HPLC-UV Method in Pasteurized Milk

The antibiotic residues in milk are a well-known serious problem and pose several health hazards to consumers. We have described a simple, rapid, and inexpensive DLLME-HPLC/UV technique for the extraction of chloramphenicol and florfenicol residues in milk samples. Under the optimum conditions, linearity of the method was observed over the range 0.02-0.85 µg/L with correlation coefficients > 0....

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Evaluation of Antibacterial Properties of Magnetic Iron Oxide Nanoparticles Synthesized using Echinops Persicus Extract Coated with Chloramphenicol

Introduction: The use of plants is one of the most effective methods for the synthesis of nanoparticles based on green chemistry. The magnetic properties of nanoparticles let the attached drugs conduct by a magnetic field in the body. This study aimed to use the magnetic iron oxide nanoparticles synthesized via green chemistry as a carrier for the chloramphenicol drug delivery system.   Materi...

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Chloramphenicol acetyltransferase should not provide methanogens with resistance to chloramphenicol.

Growth of the four methanogens investigated was inhibited by chloramphenicol-3-acetate; therefore, introduction of chloramphenicol acetyltransferase-encoding genes should not confer chloramphenicol resistance on these methanogens. Reduction of the aryl nitro group of chloramphenicol produced a compound which did not inhibit the growth of these methanogens.

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Htibacterial activity ceftizoxime and its comparison with that of chloramphenicol, penicillin G, cephalexin, cefzoline and cephalothin

This study compares the inhibitory effect of ceftizoxime with that of penicillin G, chloramphenicol, cephalothin, cephalexin and cefzoline on Klebsiella pneumoniae, Proteus mirabilis, pseudomonas ruginosa, staphylococcus aureus, staphylococcus epidermidis, staphylococcus saprophyticus and Escherichia coli. The in vitro inhibitory effect of ceftizoxime on P. mirabilis, P. Aeruginosa, S.prophytic...

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عنوان ژورنال:
  • Bacteriological reviews

دوره 25 1  شماره 

صفحات  -

تاریخ انتشار 1961